North ML, Amatullah H, Khanna N, Urch B, Grasemann H, Silverman F, Scott JA. Respir Res. 2011 Feb 3;12:19. ABSTRACT: BACKGROUND: Arginase overexpression contributes to airways hyperresponsiveness (AHR) in asthma. Arginase expression is further augmented in cigarette smoking asthmatics, sugg
Sivagangabalan G, Spears D, Masse S, Urch B, Brook RD, Silverman F, Gold DR, Lukic KZ, Speck M, Kusha M, Farid T, Poku K, Shi E,Floras J, Nanthakumar K. J Am Coll Cardiol. 2011 Jan 11;57(2):198-206. ABSTRACT: OBJECTIVES: We tested the hypothesis that exposure to concentrated ambient par
The 4th Jack Pepys Work-related Asthma Workshop on Work-related asthma and airway diseases, co-chaired by Dr Susan M Tarlo, University of Toronto and Dr Jean-Luc Malo, Université de Montréal, was held 14th May 2010 at the University of Toronto at the Munk International Centre. Co-sponsors were t
Many allergens in the workplace continue to cause both occupational allergic contact dermatitis (OACD) and occupational allergic asthma (OAA). Often, the same chemical may cause OAA in one worker and OACD in another. In order to prevent occupational allergic skin or lung disease we need to under
Akhtar US, McWhinney RD, Rastogi N, Abbatt JP, Evans GJ, Scott JA. Inhal Toxicol. 2010 Dec;22 Suppl 2:37-47. ABSTRACT: The composition of airborne particulate matter (PM) varies widely depending on its source, and recent studies have suggested that particle-associated adverse health effects are
Hoy RF, Ribeiro M, Anderson J, Tarlo SM. Occup Med (Lond). 2010 Oct;60(7):546-51. ABSTRACT: BACKGROUND: Work-associated respiratory symptoms may be caused by disorders of both the lower and upper respiratory tract. We propose that occupational exposures may initiate and/or trigger recurrent hyp
Verma DK, Demers C, Shaw D, Verma P, Kurtz L, Finkelstein M, des Tombe K, Welton T. J Environ Public Health. 2010;2010:526487. Epub 2011 Jan 3. ABSTRACT: A pilot study was conducted within the Ontario sawmill and veneer/plywood manufacturing industry. Information was collected by postal ques
Liss GM, Buyantseva L, Luce CE, Ribeiro M, Manno M, Tarlo SM. Am J Ind Med. 2011 Apr;54(4):278-84. doi: 10.1002/ajim.20935. Epub 2011 Feb 15. ABSTRACT: BACKGROUND: The health of workers in health care has been neglected in the past. There are few reports regarding occupational asthma (
Tarlo SM, Liss GM. Current Allergy and Asthma Reports 2010; 10:278-286. ABSTRACT: Prevention of occupational asthma related to a work-sensitizing agent ideally would be achieved by avoidance of exposures that cause immunologic sensitization and subsequent asthma. There are a few examples in whic