Publications

Perception of asthma as a factor in career choice among young adults with asthma.

Bhinder S, Cicutto L, Abdel-Qadir HM, Tarlo SM. Can Respir J. 2009 Nov-Dec;16(6):e69-75. ABSTRACT: Background: Asthma is a common chronic condition that can be aggravated by workplace exposures. Young adults with asthma should know how their future occupation might affect their asthma...

Work-related asthma: A case-based guide.

Tarlo SM, Cartier A; Canadian Thoracic Society Asthma Committee. Can Respir J. 2009 Nov-Dec;16(6):e57-61. ABSTRACT: Work-related asthma is common yet underdiagnosed. It is a significant cause of morbidity and socioeconomic loss. Diagnosis is often difficult, and requires a strong index of...

CR3 (CD11b/CD18) activation of nasal neutrophils: a measure of upper airway endotoxin exposure.

Seth R, Romaschin AD, Ribeiro M, Tarlo SM. Biomarkers. 2009 Nov;14(7):473-9. ABSTRACT: Inhaled endotoxin (lipopolysaccharide, LPS) initiates an inflammatory response and leads to the expression of CR3 (CD11b/CD18) receptors on polymorphonuclear leukocytes (PMNs). We determined if PMN activation in nasal lavage...

How to diagnose and treat work-related asthma: key messages for clinical practice from the American college of chest physicians consensus statement.

Tarlo SM, Liss GM, Blanc PD. Pol Arch Med Wewn. 2009 Oct;119(10):660-6. ABSTRACT: Work-related asthma is common among adult asthmatics, either asthma initially caused by work (occupational asthma) or pre-existing asthma worsened by work factors (work-exacerbated asthma). Appropriate management...

An official ATS proceedings: asthma in the workplace: the Third Jack Pepys Workshop on Asthma in the Workplace: answered and unanswered questions.

Tarlo SM, Malo JL; Third Jack Pepys Workshop on Asthma in the Workplace Participants. Proc Am Thorac Soc. 2009 Aug 1;6(4):339-49. ABSTRACT: The Third Jack Pepys Workshop on Asthma in the Workplace held in Montreal, Canada in May 2007 focused on emerging data, including progress over the...

Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans.

Brook RD, Urch B, Dvonch JT, Bard RL, Speck M, Keeler G, Morishita M, Marsik FJ, Kamal AS, Kaciroti N, Harkema J, Corey P,Silverman F, Gold DR, Wellenius G, Mittleman MA, Rajagopalan S, Brook JR. Hypertension. 2009 Sep;54(3):659-67. Epub 2009 Jul 20. ABSTRACT: Fine particulate matter air...

Predicting the need for supplemental oxygen during airline flight in patients with chronic pulmonary disease: a comparison of predictive equations and altitude simulation.

Bradi AC, Faughnan ME, Stanbrook MB, Deschenes-Leek E, Chapman KR. Can Respir J. 2009 Jul-Aug;16(4):119-24. BACKGROUND: Patients with chronic pulmonary diseases are at increased risk of hypoxemia when travelling by air. Screening guidelines, predictive equations based on ground level measurements...

Cutaneous and respiratory symptoms among professional cleaners.

Occup Med (Lond). 2009 Jun;59(4):249-54. Epub 2009 May 11. Lynde CB, Obadia M, Liss GM, Ribeiro M, Holness DL, Tarlo SM. BACKGROUND: Occupational dermatitis is very common and has a large economic impact. Cleaners are at an increased risk for both work-related cutaneous and respiratory symptoms. AIMS:...

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma.

North ML, Khanna N, Marsden PA, Grasemann H, Scott JA. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L911-20. Epub 2009 Mar 13. ABSTRACT: l-Arginine metabolism by the arginase and nitric oxide (NO) synthase (NOS) families of enzymes is important in NO production, and imbalances between...

Epidemiology of asthma: risk factors for development.

Subbarao P, Becker A, Brook JR, Daley D, Mandhane PJ, Miller GE, Turvey SE, Sears MR. Expert Rev Clin Immunol. 2009 Jan;5(1):77-95. ABSTRACT: This comprehensive review of the recent literature was undertaken to determine the current state of knowledge of the risk factors involved in the development of asthma in...