Occupational Lung Disease

Predicting the need for supplemental oxygen during airline flight in patients with chronic pulmonary disease: a comparison of predictive equations and altitude simulation.

Bradi AC, Faughnan ME, Stanbrook MB, Deschenes-Leek E, Chapman KR. Can Respir J. 2009 Jul-Aug;16(4):119-24. BACKGROUND: Patients with chronic pulmonary diseases are at increased risk of hypoxemia when travelling by air. Screening guidelines, predictive equations based on ground level measurement

Consensus on work-related asthma.

Tarlo SM, Rowe B, Liss GM, Lemiere C, Beach J. Occup Med (Lond). 2009 Jun;59(4):213-5. PubMed link to article

Cutaneous and respiratory symptoms among professional cleaners.

Lynde CB, Obadia M, Liss GM, Ribeiro M, Holness DL, Tarlo SM. Occup Med (Lond). 2009 Jun;59(4):249-54. Epub 2009 May 11. ABSTRACT: BACKGROUND: Occupational dermatitis is very common and has a large economic impact. Cleaners are at an increased risk for both work-related cutaneous and respi

American College of Chest Physicians consensus statement on the respiratory health effects of asbestos. Results of a Delphi study.

Banks DE, Shi R, McLarty J, Cowl CT, Smith D, Tarlo SM, Daroowalla F, Balmes J, Baumann M. Chest. 2009 Jun;135(6):1619-27. ABSTRACT: BACKGROUND: The diagnosis of and criteria for the evaluation of asbestos-related disease impairment remains controversial after decades of research. Assessing

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma.

North ML, Khanna N, Marsden PA, Grasemann H, Scott JA. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L911-20. Epub 2009 Mar 13. ABSTRACT: l-Arginine metabolism by the arginase and nitric oxide (NO) synthase (NOS) families of enzymes is important in NO production, and imbalances between

Epidemiology of asthma: risk factors for development.

Subbarao P, Becker A, Brook JR, Daley D, Mandhane PJ, Miller GE, Turvey SE, Sears MR. Expert Rev Clin Immunol. 2009 Jan;5(1):77-95. ABSTRACT: This comprehensive review of the recent literature was undertaken to determine the current state of knowledge of the risk factors involved in the de

A cohort study of traffic-related air pollution and mortality in Toronto, Ontario, Canada.

Jerrett M, Finkelstein MM, Brook JR, Arain MA, Kanaroglou P, Stieb DM, Gilbert NL, Verma D, Finkelstein N, Chapman KR, Sears MR. Environ Health Perspect. 2009 May;117(5):772-7. Epub 2009 Jan 5. BACKGROUND: Chronic exposure to traffic-related air pollution (TRAP) may contribute to premat

Key exposures and industries causing work-related contact dermatitis

We used the North American Contact Dermatitis Group (NACDG) database, which now includes occupational factors, to identify common occupational contact allergens. We then linked this information to the respiratory literature to identify whether these agents caused occupational asthma (OA). We also as

Practice patterns of pulmonologists and family physicians for occupational asthma.

Holness DL, Tabassum S, Tarlo SM, Liss GM, Silverman F, Manno M. Chest. 2007 Nov;132(5):1526-31. Epub 2007 Sep 21. BACKGROUND: The longer the duration of symptoms of occupational asthma (OA) before diagnosis, the poorer the outcome. Physicians can play a key role in the early recognition of occ

Inducible NO synthase (iNOS) in human neutrophils but not pulmonary microvascular endothelial cells (PMVEC) mediates septic protein leak in vitro.

Shelton JL, Wang L, Cepinskas G, Sandig M, Scott JA, North ML, Inculet R, Mehta S. Microvasc Res. 2007 Jul;74(1):23-31. Epub 2007 Mar 12. ABSTRACT: Sepsis-induced acute lung injury (ALI) is characterized by injury of the pulmonary microvascular endothelial cells (PMVEC) leading to high-prote