Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma.

North ML, Amatullah H, Khanna N, Urch B, Grasemann H, Silverman F, Scott JA. Respir Res. 2011 Feb 3;12:19. ABSTRACT: BACKGROUND: Arginase overexpression contributes to airways hyperresponsiveness (AHR) in asthma. Arginase expression is further augmented in cigarette smoking asthmatics, sugg