2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.

Ilies M, Di Costanzo L, North ML, Scott JA, Christianson DW. J Med Chem. 2010 May 27;53(10):4266-76. ABSTRACT: Arginase, a key metalloenzyme of the urea cycle that converts L-arginine into L-ornithine and urea, is presently considered a pharmaceutical target for the management of diseases associ

Noise-induced hearing loss in construction workers being assessed for hand-arm vibration syndrome.

House RA, Sauvé JT, Jiang D. Can J Public Health. 2010 May-Jun;101(3):226-9. ABSTRACT: BACKGROUND: Construction workers are at risk of noise-induced hearing loss (NIHL) but often have no periodic audiometric testing. METHODS: The participants were construction workers assessed for Hand-Ar

Exposure assessment in cohort studies of childhood asthma.

Arrandale VH, Brauer M, Brook JR, Brunekreef B, Gold DR, London SJ, Miller JD, Özkaynak H, Ries NM, Sears MR, Silverman FS,Takaro TK. Environ Health Perspect. 2011 May;119(5):591-7. Epub 2010 Nov 16. ABSTRACT: BACKGROUND: The environment is suspected to play an important role in the deve