Archives For: May 2010

2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.

May 15, 2010 - 10:54 am

Ilies M, Di Costanzo L, North ML, Scott JA, Christianson DW. J Med Chem. 2010 May 27;53(10):4266-76. ABSTRACT: Arginase, a key metalloenzyme of the urea cycle that converts L-arginine into L-ornithine and urea, is presently considered a pharmaceutical target for the management of diseases associated...

Noise-induced hearing loss in construction workers being assessed for hand-arm vibration syndrome.

May 14, 2010 - 10:34 am

House RA, Sauvé JT, Jiang D. Can J Public Health. 2010 May-Jun;101(3):226-9. ABSTRACT: BACKGROUND: Construction workers are at risk of noise-induced hearing loss (NIHL) but often have no periodic audiometric testing. METHODS: The participants were construction workers assessed for Hand-Arm...

Exposure assessment in cohort studies of childhood asthma.

May 14, 2010 - 10:24 am

Arrandale VH, Brauer M, Brook JR, Brunekreef B, Gold DR, London SJ, Miller JD, Özkaynak H, Ries NM, Sears MR, Silverman FS,Takaro TK. Environ Health Perspect. 2011 May;119(5):591-7. Epub 2010 Nov 16. ABSTRACT: BACKGROUND: The environment is suspected to play an important role in the development...