CREOD

Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with cystic fibrosis.

Grasemann H, Al-Saleh S, Scott JA, Shehnaz D, Mehl A, Amin R, Rafii M, Pencharz P, Belik J, Ratjen F. Am J Respir Crit Care Med. 2011 May 15;183(10):1363-8. Epub 2011 Jan 28. ABSTRACT: RATIONALE: Airway nitric oxide is reduced in cystic fibrosis airways. Asymmetric dimethylarginine is an


Mortality in Vermont granite workers and its association with silica exposure.

Vacek PM, Verma DK, Graham WG, Callas PW, Gibbs GW. Occup Environ Med. 2011 May;68(5):312-8. Epub 2010 Sep 19. ABSTRACT: OBJECTIVES: To assess mortality in Vermont granite workers and examine relationships between silica exposure and mortality from lung cancer, kidney cancer, non-malignan


Factors associated with severe versus mild immunotherapy-related systemic reactions: a case-referent study.

Liss GM, Murphy-Berendts K, Epstein T, Bernstein DI. J Allergy Clin Immunol. 2011 May;127(5):1298-300. Epub 2011 Feb 18. PubMed link to article


Vasospasm in the feet in workers assessed for HAVS.

House R, Jiang D, Thompson A, Eger T, Krajnak K, Sauvé J, Schweigert M. Occup Med (Lond). 2011 Mar;61(2):115-20. Epub 2010 Dec 31. ABSTRACT: BACKGROUND: Previous studies have suggested that the presence of the vascular component of hand-arm vibration syndrome (HAVS) in the hands increases


Global Workshop on Occupational Skin Disease, 22-23 February 2011, Geneva

A Global Workshop on Occupational Skin Disease (OSD) was held in Geneva February 22 and 23, 2011, organized by the World Health Organization and the European Academy for Dermatology and Venerology. The workshop reviewed current activity related to primary and secondary prevention of OSD. 24 invited


Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma.

North ML, Amatullah H, Khanna N, Urch B, Grasemann H, Silverman F, Scott JA. Respir Res. 2011 Feb 3;12:19. ABSTRACT: BACKGROUND: Arginase overexpression contributes to airways hyperresponsiveness (AHR) in asthma. Arginase expression is further augmented in cigarette smoking asthmatics, sugg


The effect of air pollution on spatial dispersion of myocardial repolarization in healthy human volunteers.

Sivagangabalan G, Spears D, Masse S, Urch B, Brook RD, Silverman F, Gold DR, Lukic KZ, Speck M, Kusha M, Farid T, Poku K, Shi E,Floras J, Nanthakumar K. J Am Coll Cardiol. 2011 Jan 11;57(2):198-206. ABSTRACT: OBJECTIVES: We tested the hypothesis that exposure to concentrated ambient par


New HAVS publication: “Vibration-white foot: a case report”

CREOD scientist Dr. Aaron Thompson describes the case of a 54 year-old miner with “vibration white foot”, a debilitating condition associated with foot-transmitted vibration exposure. Thompson AM, House R, Krajnak K, Eger T. Occup Med (Lond). 2010 Oct;60(7):572-4. Link to PubMed


Occupational endotoxin exposure and a novel luminol-enhanced chemiluminescence assay of nasal lavage neutrophil activation.

Seth R, Ribeiro M, Romaschin A, Scott JA, Manno M, Scott JA, Liss GM, Tarlo SM. J Allergy Clin Immunol. 2011 Jan;127(1):272-5. Epub 2010 Nov 18. PubMed link to article


Jack Pepys Work-related Asthma Workshop, May 14, 2010

The 4th Jack Pepys Work-related Asthma Workshop on Work-related asthma and airway diseases, co-chaired by Dr Susan M Tarlo, University of Toronto and Dr Jean-Luc Malo, Université  de Montréal, was held 14th May 2010 at the University of Toronto at the Munk International Centre. Co-sponsors were t